Have tried two or more antidepressants without significant improvement
Spravato® Treatment in Tuscaloosa, AL
When antidepressants have not provided the relief you need, Spravato offers a clinically proven alternative. At Novus, we offer Spravato treatment in Tuscaloosa, Alabama, for adults with treatment-resistant depression who are ready to try something different.
Insurances We Accept
Spravato for Treatment-Resistant Depression
Spravato (esketamine) is an FDA-approved prescription nasal spray for adults with treatment-resistant depression. Unlike traditional antidepressants, Spravato targets the brain's glutamate system rather than serotonin or norepinephrine. This distinct mechanism allows it to work faster and reach patients who have not responded to other medications.
Why Spravato
Research-Backed
Studied in adults with treatment-resistant depression and adults with major depressive disorder with suicidal ideation or behavior.
Faster Symptom Relief
Greater reduction of depressive symptoms in 4 weeks compared to those who received a placebo and oral antidepressant.†
Lasting Results
In clinical trials, after 16 weeks of therapy, patients who stayed on Spravato plus their oral antidepressant were less likely to experience a return of depressive symptoms compared to those who stopped therapy.‡
†In clinical trials of adults who took Spravato and an oral antidepressant compared to those who received a placebo and an oral antidepressant. Based on an overall score on a standardized rating scale.
‡Along with an oral antidepressant.
Who Can Benefit From Spravato
Spravato may be right for you if you:
Our team will conduct a thorough diagnostic evaluation to determine whether Spravato is clinically appropriate for you before any treatment begins.
What to Expect During Your Visit
Administering the Medication
Each session takes place in our Tuscaloosa offices. You apply the nasal spray yourself, with our clinical team present throughout the process. It is normal to experience some temporary effects during and shortly after administration, including:
These effects are expected and are closely monitored by our team.
Monitoring After Treatment
Once you have administered the medication, you will remain in our office for approximately two hours. During this time, our team tracks:
Before You Leave
When our team confirms you are stable, you will be cleared to go. Please note that you will not be able to drive yourself home following a Spravato session. You will need to arrange transportation in advance.
Spravato Treatment Schedule
Weeks 1 to 4:
Twice per week
After the first month:
Once per week or once every two weeks
depending on your response
Expert Care, Ready When You Are
Our team is here to listen, evaluate, and get you the care you need.
Request an Appointment ➔